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Founders & research

Behind every idea is a person. Here are the founders that brought 2FX-Complex to life.

Meet our founders

A mother and son with a shared passion for science, nature, and purposeful innovation.

What started as research into plant-based healing led to the discovery of the 2FX-complex — a smart, microbiome-friendly solution that protects the body’s natural balance.

“Innovation should never fight the body — it should work with it.”

Floris Koumans SeniorCo-Founder

Annelize Goedbloed

Floris Koumans Senior 

A scientific breakthrough born from nature

In the 1980s, medical biologist Annelize Goedbloed began exploring the properties of natural polysaccharides found in Aloe Barbadensis Miller. Her goal: to find a plant-based substance that could support the body’s own microbiome without harming beneficial bacteria.

Together with her son Floris, she launched an ambitious five-year research program in collaboration with the Free University of Amsterdam. The result was the discovery of the 2FX-complex—a bio-active substance capable of selectively neutralising harmful microbes while preserving the body’s natural flora.

This groundbreaking complex marked a shift in thinking: from killing bacteria to restoring balance, naturally and effectively.

Patented worldwide
Patent number
(WO 2022/084455 A1)

CAS-number
CAS 1609655-76-6

Certified
Under ISO 13485 (Medical Device)

2FX-complex: protecting balance, not destroying it

Unlike traditional antimicrobial agents that indiscriminately kill both harmful and beneficial microorganisms, 2FX-complex works with the body’s natural systems. Its structure is designed to block the adhesion of harmful microbes to human tissue—acting as a biological filter—without disrupting the healthy flora essential to overall wellbeing.

Today, 2FX is the core active ingredient in a range of self-care products trusted by millions worldwide. Backed by scientific validation and international patents, 2FX-complex offers a new standard in microbiome protection: gentle, effective, and smart.

The research behind 2FX continues. Our dedicated team remains focused on improving formulations, validating efficacy through clinical trials, and ensuring our products meet the highest standards in natural, science-based care.

Our research partners.

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